Publications

2019

Rifaie-Graham, O., Pollard, J., Raccio, S., Balog, S., Rusch, S., Hernandez-Castaneda, M. A., Mantel, P. Y., Beck, H. P., and Bruns, N. (2019) Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis. Nat Commun 10, 1369

2018

Babatunde, K. A., Mbagwu, S., Hernandez-Castaneda, M. A., Adapa, S. R., Walch, M., Filgueira, L., Falquet, L., Jiang, R. H. Y., Ghiran, I., and Mantel, P. Y. (2018) Malaria infected red blood cells release small regulatory RNAs through extracellular vesicles. Sci Rep 8, 884
Aurore, V., Caldana, F., Blanchard, M., Kharoubi Hess, S., Lannes, N., Mantel, P. Y., Filgueira, L., and Walch, M. (2018) Silver-nanoparticles increase bactericidal activity and radical oxygen responses against bacterial pathogens in human osteoclasts. Nanomedicine 14, 601-607
Andrea Hernandez-Castaneda, M., Mbagwu, S., Babatunde, K. A., Walch, M., Filgueira, L., and Mantel, P. Y. (2018) Evaluation of Extracellular Vesicle Function During Malaria Infection. J Vis Exp

2017

Mbagwu, S., Walch, M., Filgueira, L., and Mantel, P. Y. (2017) Production and Characterization of Extracellular Vesicles in Malaria. Methods Mol Biol 1660, 377-388
Leon, D. L., Fellay, I., Mantel, P. Y., and Walch, M. (2017) Killing Bacteria with Cytotoxic Effector Proteins of Human Killer Immune Cells: Granzymes, Granulysin, and Perforin. Methods Mol Biol 1535, 275-284

2016

Obaldia, N., 3rd, Dow, G. S., Gerena, L., Kyle, D., Otero, W., Mantel, P. Y., Baro, N., Daniels, R., Mukherjee, A., Childs, L. M., Buckee, C., Duraisingh, M. T., Volkman, S. K., Wirth, D. F., and Marti, M. (2016) Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model. Sci Rep 6, 21216
Mantel, P. Y., Hjelmqvist, D., Walch, M., Kharoubi-Hess, S., Nilsson, S., Ravel, D., Ribeiro, M., Gruring, C., Ma, S., Padmanabhan, P., Trachtenberg, A., Ankarklev, J., Brancucci, N. M., Huttenhower, C., Duraisingh, M. T., Ghiran, I., Kuo, W. P., Filgueira, L., Martinelli, R., and Marti, M. (2016) Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria. Nat Commun 7, 12727
Danielson, K. M., Estanislau, J., Tigges, J., Toxavidis, V., Camacho, V., Felton, E. J., Khoory, J., Kreimer, S., Ivanov, A. R., Mantel, P. Y., Jones, J., Akuthota, P., Das, S., and Ghiran, I. (2016) Diurnal Variations of Circulating Extracellular Vesicles Measured by Nano Flow Cytometry. PLoS One 11, e0144678

2015

Pelle, K. G., Jiang, R. H., Mantel, P. Y., Xiao, Y. P., Hjelmqvist, D., Gallego-Lopez, G. M., A, O. T. L., Kang, B. H., Allred, D. R., and Marti, M. (2015) Shared elements of host-targeting pathways among apicomplexan parasites of differing lifestyles. Cell Microbiol 17, 1618-1639
Gulati, S., Ekland, E. H., Ruggles, K. V., Chan, R. B., Jayabalasingham, B., Zhou, B., Mantel, P. Y., Lee, M. C., Spottiswoode, N., Coburn-Flynn, O., Hjelmqvist, D., Worgall, T. S., Marti, M., Di Paolo, G., and Fidock, D. A. (2015) Profiling the Essential Nature of Lipid Metabolism in Asexual Blood and Gametocyte Stages of Plasmodium falciparum. Cell Host Microbe 18, 371-381

2014

Mantel, P. Y., and Marti, M. (2014) The role of extracellular vesicles in Plasmodium and other protozoan parasites. Cell Microbiol 16, 344-354
Ankarklev, J., Brancucci, N. M., Goldowitz, I., Mantel, P. Y., and Marti, M. (2014) Sex: how malaria parasites get turned on. Curr Biol 24, R368-370

2013

Pelle, K. G., Ahouidi, A. D., and Mantel, P. Y. (2013) [Role of microvesicles in malaria infections]. Med Sci (Paris) 29, 960-962
Momen-Heravi, F., Balaj, L., Alian, S., Mantel, P. Y., Halleck, A. E., Trachtenberg, A. J., Soria, C. E., Oquin, S., Bonebreak, C. M., Saracoglu, E., Skog, J., and Kuo, W. P. (2013) Current methods for the isolation of extracellular vesicles. Biol Chem 394, 1253-1262
Mantel, P. Y., Hoang, A. N., Goldowitz, I., Potashnikova, D., Hamza, B., Vorobjev, I., Ghiran, I., Toner, M., Irimia, D., Ivanov, A. R., Barteneva, N., and Marti, M. (2013) Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system. Cell Host Microbe 13, 521-534

2011

Soligo, M., Camperio, C., Caristi, S., Scotta, C., Del Porto, P., Costanzo, A., Mantel, P. Y., Schmidt-Weber, C. B., and Piccolella, E. (2011) CD28 costimulation regulates FOXP3 in a RelA/NF-kappaB-dependent mechanism. Eur J Immunol 41, 503-513
Morahan, B. J., Strobel, C., Hasan, U., Czesny, B., Mantel, P. Y., Marti, M., Eksi, S., and Williamson, K. C. (2011) Functional analysis of the exported type IV HSP40 protein PfGECO in Plasmodium falciparum gametocytes. Eukaryot Cell 10, 1492-1503
Mantel, P. Y., and Schmidt-Weber, C. B. (2011) Transforming growth factor-beta: recent advances on its role in immune tolerance. Methods Mol Biol 677, 303-338

2010

Burgler, S., Mantel, P. Y., Bassin, C., Ouaked, N., Akdis, C. A., and Schmidt-Weber, C. B. (2010) RORC2 is involved in T cell polarization through interaction with the FOXP3 promoter. J Immunol 184, 6161-6169

2009

Ouaked, N., Mantel, P. Y., Bassin, C., Burgler, S., Siegmund, K., Akdis, C. A., and Schmidt-Weber, C. B. (2009) Regulation of the foxp3 gene by the Th1 cytokines: the role of IL-27-induced STAT1. J Immunol 182, 1041-1049
Klunker, S., Chong, M. M., Mantel, P. Y., Palomares, O., Bassin, C., Ziegler, M., Ruckert, B., Meiler, F., Akdis, M., Littman, D. R., and Akdis, C. A. (2009) Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells. J Exp Med 206, 2701-2715
Burgler, S., Ouaked, N., Bassin, C., Basinski, T. M., Mantel, P. Y., Siegmund, K., Meyer, N., Akdis, C. A., and Schmidt-Weber, C. B. (2009) Differentiation and functional analysis of human T(H)17 cells. J Allergy Clin Immunol 123, 588-595, 595 e581-587

2007

Saruta, M., Yu, Q. T., Fleshner, P. R., Mantel, P. Y., Schmidt-Weber, C. B., Banham, A. H., and Papadakis, K. A. (2007) Characterization of FOXP3+CD4+ regulatory T cells in Crohn’s disease. Clin Immunol 125, 281-290
Mantel, P. Y., Kuipers, H., Boyman, O., Rhyner, C., Ouaked, N., Ruckert, B., Karagiannidis, C., Lambrecht, B. N., Hendriks, R. W., Crameri, R., Akdis, C. A., Blaser, K., and Schmidt-Weber, C. B. (2007) GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells. PLoS Biol 5, e329
Basinski, T., Ozdemir, C., Sackesen, C., Mantel, P. Y., Barlan, I., Akdis, M., Jutel, M., and Akdis, C. A. (2007) Highlights in cellular and molecular mechanisms of allergic diseases. XXVth Congress of the European Academy of Allergology and Clinical Immunology in Vienna. Int Arch Allergy Immunol 142, 91-98

2006

Mantel, P. Y., Ouaked, N., Ruckert, B., Karagiannidis, C., Welz, R., Blaser, K., and Schmidt-Weber, C. B. (2006) Molecular mechanisms underlying FOXP3 induction in human T cells. J Immunol 176, 3593-3602
Karagiannidis, C., Hense, G., Rueckert, B., Mantel, P. Y., Ichters, B., Blaser, K., Menz, G., and Schmidt-Weber, C. B. (2006) High-altitude climate therapy reduces local airway inflammation and modulates lymphocyte activation. Scand J Immunol 63, 304-310
Karagiannidis, C., Hense, G., Martin, C., Epstein, M., Ruckert, B., Mantel, P. Y., Menz, G., Uhlig, S., Blaser, K., and Schmidt-Weber, C. B. (2006) Activin A is an acute allergen-responsive cytokine and provides a link to TGF-beta-mediated airway remodeling in asthma. J Allergy Clin Immunol 117, 111-118

2004

Karagiannidis, C., Akdis, M., Holopainen, P., Woolley, N. J., Hense, G., Ruckert, B., Mantel, P. Y., Menz, G., Akdis, C. A., Blaser, K., and Schmidt-Weber, C. B. (2004) Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma. J Allergy Clin Immunol 114, 1425-1433

2003

Kunzmann, S., Mantel, P. Y., Wohlfahrt, J. G., Akdis, M., Blaser, K., and Schmidt-Weber, C. B. (2003) Histamine enhances TGF-beta1-mediated suppression of Th2 responses. FASEB J 17, 1089-1095
Finney, N., Walther, F., Mantel, P. Y., Stauffer, D., Rovelli, G., and Dev, K. K. (2003) The cellular protein level of parkin is regulated by its ubiquitin-like domain. J Biol Chem 278, 16054-16058